Finding and Developing Natural Products for New Medicines
Discovery and Characterization of Natural Product Systems
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11083675
This work explores natural compounds from bacteria and fungi to create new medicines, especially for infections that are hard to treat.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11083675 on ClinicalTrials.gov |
What this research studies
Our team is looking into how bacteria and fungi naturally create complex molecules that could become powerful new drugs. We are learning how these tiny organisms build these compounds, focusing on specific parts of their cellular machinery. By understanding and even modifying these natural processes, we hope to develop new types of antibiotics and other treatments. This approach could lead to breakthroughs for patients battling infections that no longer respond to current medications.
Who could benefit from this research
Good fit: Future patients suffering from bacterial infections, particularly those resistant to current antibiotics, are the ultimate beneficiaries of this foundational research.
Not a fit: Patients not experiencing bacterial infections or those whose conditions are unrelated to natural product-derived therapies would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to the discovery and development of entirely new antibiotics and other therapeutic agents to combat drug-resistant infections.
How similar studies have performed: This program has been highly productive with many publications, indicating a strong track record in this area of natural product discovery and characterization.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHERMAN, DAVID H — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: SHERMAN, DAVID H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.