Finding and controlling hidden malaria infections in India
Center for the Study of Complex Malaria in India
['FUNDING_OTHER'] · LONDON SCH/HYGIENE & TROPICAL MEDICINE · NIH-11393237
This center works with Indian communities to find malaria infections that current tests miss and to improve tools for stopping transmission.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LONDON SCH/HYGIENE & TROPICAL MEDICINE (nih funded) |
| Locations | 1 site (LONDON, UNITED KINGDOM) |
| Trial ID | NIH-11393237 on ClinicalTrials.gov |
What this research studies
From a patient's view, researchers follow adults in three districts of Odisha for several years and collect blood samples and symptom information to find hidden infections. They will also track people who come to district health centers with fevers to see where tests fail and why. The team uses lab assays, antibody and biomarker work, and genomic tools to detect low-level and hard-to-find malaria parasites. The center also supports training and builds local research capacity so Indian programs can use the findings.
Who could benefit from this research
Good fit: Adults (21+) living in the study districts of Odisha, India, especially those with recent fevers or who are part of the community cohort, are the ideal participants.
Not a fit: Children under 21, people living outside the study districts, or those not seen at participating health centers would not directly benefit from enrolling in this project.
Why it matters
Potential benefit: If successful, this work could help health workers detect infections current tests miss and reduce ongoing malaria spread in affected communities.
How similar studies have performed: Community cohorts and molecular detection methods have previously found hidden malaria infections in other settings, but combining long-term cohorts, passive clinic surveillance, and biomarker discovery in India is relatively new.
Where this research is happening
LONDON, UNITED KINGDOM
- LONDON SCH/HYGIENE & TROPICAL MEDICINE — LONDON, UNITED KINGDOM (ACTIVE)
Researchers
- Principal investigator: WASSMER, SAM — LONDON SCH/HYGIENE & TROPICAL MEDICINE
- Study coordinator: WASSMER, SAM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.