NIH-funded research NIH-funded research

Finding and controlling hidden malaria infections in India

Official title: Center for the Study of Complex Malaria in India

Funded at London Sch/hygiene & Tropical Medicine · NIH-11393237 · Data updated 2026-11-12

This center works with Indian communities to find malaria infections that current tests miss and to improve tools for stopping transmission.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLondon Sch/hygiene & Tropical Medicine
NIH-funded
Lab location1 site (London, United Kingdom)
Project startAugust 20, 2024
Project endMay 31, 2029
Funding year2025
Award (this year)$226,734
NIH project number3U19AI181587-02S1
Project IDNIH-11393237 on NIH RePORTER

Who could benefit from this research

Could help

Adults (21+) living in the study districts of Odisha, India, especially those with recent fevers or who are part of the community cohort, are the ideal participants.

Less likely to help

Children under 21, people living outside the study districts, or those not seen at participating health centers would not directly benefit from enrolling in this project.

What this research studies

From a patient's view, researchers follow adults in three districts of Odisha for several years and collect blood samples and symptom information to find hidden infections. They will also track people who come to district health centers with fevers to see where tests fail and why. The team uses lab assays, antibody and biomarker work, and genomic tools to detect low-level and hard-to-find malaria parasites. The center also supports training and builds local research capacity so Indian programs can use the findings.

Why it matters

Potential benefit: If successful, this work could help health workers detect infections current tests miss and reduce ongoing malaria spread in affected communities.

How similar studies have gone: Community cohorts and molecular detection methods have previously found hidden malaria infections in other settings, but combining long-term cohorts, passive clinic surveillance, and biomarker discovery in India is relatively new.

Where this research is happening

  • London Sch/hygiene & Tropical Medicine
    London, United Kingdom
    Active

Researchers

  • Principal investigator: Wassmer, Sam — London Sch/hygiene & Tropical Medicine
  • Study coordinator: Wassmer, Sam

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.