Finalizing the Ovaprene vaginal device trial for contraception

PROTOCOL FINALIZATION, PROCUREMENT OF REGULATORY APPROVAL, AND COMPLETE START-UP ACTIVITIES FOR THE OVAPRENE VAGINAL DEVICE CLINICAL TRIAL

NIH-funded research Health Decisions, INC. · NIH-11250967

This study is testing a new hormone-free vaginal contraceptive called Ovaprene to see how well it works, and it's looking for about 800 women who can help by participating over the next 13 months.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionHealth Decisions, INC. NIH-funded
Lab location1 site (Morrisville, United States)
Project IDNIH-11250967 on NIH RePORTER

What this research studies

This research focuses on the Ovaprene vaginal device, a hormone-free contraceptive option designed for single-cycle use by women. The study aims to finalize the trial protocol, obtain necessary regulatory approvals, and initiate recruitment and enrollment of participants. Approximately 800 women of child-bearing age will be involved in a 13-month efficacy study to evaluate the device's effectiveness. The research is coordinated by Health Decisions, Inc., in partnership with the NICHD.

Who could benefit from this research

Good fit: Ideal candidates for participation are women of child-bearing age who are seeking non-hormonal contraceptive methods.

Not a fit: Patients who are not of child-bearing age or those who are not interested in contraceptive options may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide women with a new, safe, and effective non-hormonal contraceptive option.

How similar studies have performed: Previous research in the development of non-hormonal contraceptives has shown promise, indicating potential for success in this area.

Where this research is happening

Morrisville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.