Faster high-resolution diffusion MRI using data redundancy
Official title: Fast High-Resolution Microstructure Diffusion MRI Exploiting Data Redundancy
Funded at New York University School of Medicine · NIH-11563816 · Data updated 2026-11-12
A new MRI method aims to speed up brain scans by using how data naturally repeats itself, so patients can get clearer brain images faster.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $248,999 |
| NIH project number | 4R00EB036080-03 |
| Project ID | NIH-11563816 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals requiring brain diffusion MRI, including those needing high-resolution imaging for neurological conditions.
✕Less likely to help
Patients who cannot undergo MRI or have contraindications to MRI would not benefit.
What this research studies
This grant supports developing a faster diffusion MRI technique (zero-shell imaging) that leverages data redundancy to shorten scan times while preserving image quality. The project will explore joint undersampling in both the spatial and diffusion-encoding dimensions to directly reconstruct diffusion contrasts with fewer samples. The goal is to reach up to a five-fold speed increase, enabling high-resolution (1 mm^3) brain imaging in clinical settings. If successful, this could improve diagnostics and planning for brain-related conditions without longer sessions for patients.
Why it matters
Potential benefit: Patients could benefit from much shorter scan times and sharper brain images that aid diagnosis and treatment planning.
How similar studies have gone: Previous MRI acceleration methods have shown promise, but the proposed zero-shell imaging aims for a larger, clinically meaningful speedup with preserved microstructure detail.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Coelho, Santiago — New York University School of Medicine
- Study coordinator: Coelho, Santiago
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.