NIH-funded research NIH-funded research

Family support program for teens with substance use and depression/anxiety

Official title: Testing the Feasibility of a Family-based Adjunctive Treatment Protocol for Targeting Co-Occurring Internalizing Disorders among Adolescents with SUD

Funded at Partnership to End Addiction · NIH-11312727 · Data updated 2026-11-12

This project will offer a short family-based program alongside usual care to help teens (ages 13–21) in substance use treatment who are also dealing with depression or anxiety.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPartnership to End Addiction
NIH-funded
Lab location1 site (New York, United States)
Project startApril 15, 2024
Project endMarch 31, 2027
Funding year2026
Award (this year)$243,397
NIH project number5R34DA056026-03
Project IDNIH-11312727 on NIH RePORTER

Who could benefit from this research

Could help

Teens aged 13–21 who are enrolled in community-based substance use treatment and who have co-occurring depression or anxiety, together with at least one caregiver willing to participate.

Less likely to help

This program may not help teens without co-occurring internalizing disorders, families unwilling or unable to engage in sessions, or youth who need more intensive specialty mental health care.

What this research studies

You and your family would be offered Fam-AID, a six-module family support program designed to fit alongside the treatment you already receive for substance use. The modules (including family engagement, caregiver skills, and teen coping strategies) can be delivered in any order to match your needs. The team will develop the materials, pilot the program in community treatment settings, collect feedback from families and clinicians, and measure whether the program is feasible to deliver and acceptable to participants. Results will be used to refine the program for wider use in frontline clinics.

Why it matters

Potential benefit: If successful, this program could help reduce depression and anxiety symptoms and make substance use treatment work better by giving families practical skills and support.

How similar studies have gone: Some integrated behavioral programs for co-occurring substance use and internalizing disorders have shown promise but are often intensive and hard to deliver in community settings, so this modular family approach is a newer, more scalable idea.

Where this research is happening

  • Partnership to End Addiction
    New York, United States
    Active

Researchers

  • Principal investigator: Hogue, Aaron — Partnership to End Addiction
  • Study coordinator: Hogue, Aaron

Related research

Other NIH-funded projects on the same topics.

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  • Using digital tools to help new mothers reduce substance use at home

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  • Developing a family-based treatment for teens with substance use and mental health issues

    This study is testing a new family-focused treatment called Fam-AID to help young people aged 13-21 who are struggling with both substance use and mental health issues like anxiety and depression, aiming to improve their recovery by involving their families in the process.

    NIH research Partnership to End Addiction · New York, United States · NIH-11074105

  • Helping new mothers reduce heavy drinking after childbirth

    This study is looking to help new moms who are having a tough time with drinking in the first few months after giving birth by creating a friendly digital helpline where they can chat with experts and get helpful tips to support their journey to healthier habits.

    NIH research Partnership to End Addiction · New York, United States · NIH-10983527

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.