Fallopian tube removal to prevent ovarian cancer
Salpingectomy for Ovarian Cancer Risk Reduction: Improving Utilization and Informed Decision-Making
This project uses removal of the fallopian tubes while keeping the ovaries to lower ovarian cancer risk for people having hysterectomy or choosing permanent sterilization.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11191424 on NIH RePORTER |
What this research studies
If you're having a hysterectomy or choosing permanent sterilization, doctors may be able to remove your fallopian tubes while leaving your ovaries in place to reduce ovarian cancer risk without causing early menopause. The team will study how often and why providers offer this option and how much patients know about it by collecting data from medical records and talking with patients and clinicians. They will develop and test ways to improve counseling and decision-making so people get clear information about benefits and trade-offs. The focus is on increasing appropriate use of salpingectomy while protecting quality of life.
Who could benefit from this research
Good fit: People planning a hysterectomy or permanent sterilization who want to lower ovarian cancer risk while preserving their ovaries.
Not a fit: People with very high genetic risk who are advised to remove their ovaries (for example BRCA carriers) and those not undergoing pelvic surgery are unlikely to benefit from this approach.
Why it matters
Potential benefit: Could reduce ovarian cancer risk for many people without causing surgical menopause and its related health harms.
How similar studies have performed: Research shows many ovarian cancers begin in the fallopian tubes and salpingectomy is a promising prevention approach, but efforts to boost its uptake and improve patient decision-making are still relatively new.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Xu, Xiao — Columbia University Health Sciences
- Study coordinator: Xu, Xiao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.