NIH-funded research R01 grant

Fairer ICU life-support decisions during crises using neighborhood disadvantage scores

Official title: Improving the efficiency and equity of critical care allocation during a crisis with place-based disadvantage indices

Funded at University of Chicago · NIH-11259583 · Data updated 2026-11-12

A new method uses neighborhood disadvantage scores to help hospitals decide which adults receive scarce ICU life-support during crises like COVID-19.

More Critical Care research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startApril 1, 2023
Project endJanuary 31, 2028
Funding year2026
Award (this year)$539,207
NIH project number5R01LM014263-04
Project IDNIH-11259583 on NIH RePORTER

Who could benefit from this research

Could help

Adults (age 21+) who are hospitalized with severe, potentially life-threatening illness during a disaster or whose hospital records are used for validation are the focus of this work.

Less likely to help

Children, people not hospitalized during a crisis, and patients treated at hospitals that do not adopt the protocol may not directly benefit.

What this research studies

If hospitals run out of ICU beds during disasters, triage teams often use scores like SOFA to choose who gets life support, but those scores can miss true risk before ICU care starts. This project aims to create a new allocation protocol that adjusts SOFA with place-based disadvantage indices—neighborhood measures of social and economic hardship—to reduce bias. The team will test the approach using past U.S. hospital records and statistical modeling to see if it predicts survival better and narrows geographic disparities. They will compare the new protocol to current methods to estimate how many more lives could be saved and whether outcomes become fairer across communities.

Why it matters

Potential benefit: If successful, this could save more lives and reduce unfair disadvantages for patients from poorer neighborhoods during crises with scarce ICU resources.

How similar studies have gone: SOFA-based triage is commonly used but shows known prediction and calibration problems, and adding neighborhood disadvantage measures to correct those biases is a relatively new approach with limited prior real-world testing.

Where this research is happening

  • University of Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Parker, William F — University of Chicago
  • Study coordinator: Parker, William F

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.