Extending the IGNITE network to complete clinical trials related to COVID-19.
IGNITE Cost Extension- Year 7
This study is working to get back on track with important trials that look at how genetic information can help improve health outcomes, especially for those affected by COVID-19, and it aims to involve more patients to gather valuable data for better healthcare in the future.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11078419 on NIH RePORTER |
What this research studies
This research focuses on completing the activities of the IGNITE network, specifically the trials known as GUARDD and ADOPT-PGX, which were delayed due to the COVID-19 pandemic. The project aims to finalize study protocols, address procedural challenges, and increase enrollment targets to ensure robust data collection. Patients may be involved in ongoing trials that assess the impact of genomic data on health outcomes, particularly in the context of COVID-19. The research will also include secondary analyses to publish findings that could inform future healthcare practices.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals involved in the trials or those affected by COVID-19 who may benefit from genomic insights into their health.
Not a fit: Patients who are not affected by COVID-19 or do not have a relevant genomic condition may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance understanding of how genomic data can improve patient care and treatment strategies during and after the COVID-19 pandemic.
How similar studies have performed: Other research has shown success in utilizing genomic data to inform treatment strategies, particularly in the context of complex health conditions like those exacerbated by COVID-19.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Orlando, Lori Ann — Duke University
- Study coordinator: Orlando, Lori Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.