Exploring why African Americans have worse outcomes in colorectal cancer
Understanding the Contribution of Colorectal Cancer Tumor Characteristics to Disparities in Colorectal Cancer Survival
This study is looking into why African Americans have higher death rates from colorectal cancer compared to white patients, by examining the differences in their tumors, and it hopes to find ways to improve treatment based on these findings.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10848403 on NIH RePORTER |
What this research studies
This research investigates the reasons behind the higher mortality rates of colorectal cancer (CRC) among African Americans compared to non-Hispanic whites. It focuses on understanding the biological differences in CRC tumors, such as their molecular profiles and genetic characteristics, which may contribute to these disparities. By analyzing tumor data from a large cohort of African American and white patients, the study aims to identify specific tumor traits that lead to poorer survival outcomes. Patients may benefit from insights that could inform more tailored treatment strategies based on their tumor biology.
Who could benefit from this research
Good fit: Ideal candidates for this research include African American individuals diagnosed with colorectal cancer.
Not a fit: Patients who are not diagnosed with colorectal cancer or those from racial groups other than African American may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment approaches and better survival rates for African American patients with colorectal cancer.
How similar studies have performed: Previous research has indicated that understanding tumor biology can lead to significant advancements in cancer treatment, suggesting that this approach may yield valuable insights.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Warren Andersen, Shaneda — University of Wisconsin-Madison
- Study coordinator: Warren Andersen, Shaneda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.