Exploring ways to target aging cells to improve health in older adults
Targeting Cellular Senescence to Extend Healthspan
This study is looking at how we can help people stay healthier as they age by targeting old, malfunctioning cells in the body, and it aims to find new treatments that could improve your overall well-being and quality of life.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11079485 on NIH RePORTER |
What this research studies
This research investigates how targeting cellular senescence, which is the process by which cells lose their ability to divide and function properly as we age, can help extend the healthspan of individuals. The team is exploring the mechanisms behind cellular senescence in various tissues and how pharmacological interventions can modify this process. By understanding the roles of specific senescent cell types and developing new therapies, the research aims to slow or prevent age-related diseases. Patients may benefit from potential new treatments that improve their overall health and quality of life as they age.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing age-related health issues or diseases.
Not a fit: Patients who are younger and do not have age-related conditions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly enhance the health and longevity of older adults.
How similar studies have performed: Previous research has shown promising results in targeting cellular senescence, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Lebrasseur, Nathan K — Mayo Clinic Rochester
- Study coordinator: Lebrasseur, Nathan K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.