Exploring ways to reduce negative feelings in people with chronic low back pain
Proof of concept study to treat negative affect in chronic low back pain
This study is looking at ways to help people with chronic low back pain feel better emotionally, by using a mix of therapy and medication to see if it can reduce feelings of anxiety and depression while also helping with pain.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10683413 on NIH RePORTER |
What this research studies
This research investigates methods to alleviate negative emotions such as anxiety and depression in individuals suffering from chronic low back pain. The approach combines behavioral therapies and antidepressant medications to assess their effectiveness in improving emotional well-being and pain management. Patients will be monitored throughout the treatment process to evaluate changes in their emotional state and pain levels. The study aims to provide a comprehensive understanding of how emotional health impacts chronic pain and vice versa.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic low back pain accompanied by negative emotional states such as anxiety or depression.
Not a fit: Patients who do not have chronic low back pain or those without significant emotional distress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved emotional health and pain relief for patients with chronic low back pain.
How similar studies have performed: Previous research has shown that addressing emotional health can significantly improve outcomes for patients with chronic pain, suggesting that this approach may be effective.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Wasan, Ajay D — University of Pittsburgh at Pittsburgh
- Study coordinator: Wasan, Ajay D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.