Exploring tumor environments using advanced imaging techniques
Official title: IMAT-ITCR Collaboration: Combining FIBI and topological data analysis: Synergistic approaches for tumor structural microenvironment exploration
Funded at University of California at Davis · NIH-10885376 · Data updated 2026-11-12
This study is looking at how different imaging techniques can help us better understand the environment around breast cancer tumors, with the goal of improving diagnosis and treatment for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $79,979 |
| NIH project number | 3R33CA278544-01S1 |
| Project ID | NIH-10885376 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with breast cancer who are undergoing imaging for diagnostic purposes.
✕Less likely to help
Patients with non-malignant conditions or those not undergoing imaging for breast cancer may not benefit from this research.
What this research studies
This research investigates the structural microenvironment of tumors, specifically focusing on breast cancer, by comparing two imaging techniques: Fluorescence Imitating Brightfield Imaging (FIBI) and traditional hematoxylin and eosin (H&E) staining. The study aims to utilize novel mathematical tools to quantify the differences and similarities in the images produced by these methods. By enhancing the understanding of tumor microenvironments, the research seeks to improve diagnostic capabilities and clinical outcomes for patients. The approach involves collaboration between experts at Stony Brook University and UC Davis to validate the effectiveness of FIBI as a diagnostic tool.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic imaging techniques for breast cancer, enhancing early detection and treatment strategies.
How similar studies have gone: Previous studies have shown promising results with FIBI, indicating its potential as a diagnostic tool, although this specific approach is relatively novel.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Levenson, Richard M. — University of California at Davis
- Study coordinator: Levenson, Richard M.
Related research
Other NIH-funded projects on the same topics.
-
UC Davis IGA Innovation Center
A research center at UC Davis will study gene-edited livestock to improve animal health, safety, and policy through sharing genetic data and findings about genome edits in cattle, pigs, sheep, and goats.
-
Administrative Core of an equitable breast cancer screening program
A national program headed from UC Davis is coordinating several research efforts to improve how breast cancer screening is done in community settings.
-
The role of novelty and surprise in learning for people with Alzheimer’s disease
A study explores how surprising events affect memory and learning in people related to Alzheimer’s disease, using everyday tasks to see how the brain remembers new information.
-
Understanding how distraction affects students and how to measure it better
This grant studies why distracted students, including those with ADHD, struggle in real-life learning and tests a clearer way to measure distraction in everyday settings.
-
California Partnership for Personalized Nutrition
A California clinical center is testing personalized dietary approaches to improve blood sugar and health for adults with diabetes by using big data and AI to tailor meals.
-
Advancing gastric cancer care for Latinos through patient-derived tumor models
Aimed at Latinos with gastric cancer, this project uses patient-derived tumor models to study how cancer biology and treatments work in real tumors.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.