Exploring treatments for weight loss and energy issues in cancer patients
PQ6: Therapeutic approaches for autonomic and neuroendocrine dysfunction in cancer cachexia
This study is looking into how cancer causes weight loss and muscle loss, and it aims to find ways to help improve the health and recovery of patients dealing with these tough symptoms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10897044 on NIH RePORTER |
What this research studies
This research investigates the underlying mechanisms of cancer cachexia, a condition characterized by severe weight loss and muscle wasting in cancer patients. The team aims to understand how cancer triggers neuroinflammation and affects the sympathetic nervous system, which may lead to metabolic disturbances and cardiovascular issues. By studying these processes, the researchers hope to identify potential therapeutic approaches that could improve the quality of life and recovery for patients suffering from this debilitating condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients experiencing cachexia, characterized by significant weight loss and metabolic disturbances.
Not a fit: Patients who are not diagnosed with cancer or do not exhibit symptoms of cachexia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective treatments that alleviate weight loss and improve overall health in cancer patients.
How similar studies have performed: While the mechanisms of cancer cachexia have been studied, this research aims to explore novel therapeutic approaches that have not yet been widely tested.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Grossberg, Aaron — Oregon Health & Science University
- Study coordinator: Grossberg, Aaron
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.