NIH-funded research R01 grant

Exploring time-restricted eating as an alternative to calorie counting for managing type 2 diabetes

Official title: Time Restricted Eating As a Viable Alternative to Caloric Restriction for Treating Hyperglycemia in a Population with Type 2 (T2DM) diabetes

Funded at University of Minnesota · NIH-10825524 · Data updated 2026-11-12

This study is looking at whether eating only during certain hours of the day can help people with type 2 diabetes who are overweight, and who take metformin, to better manage their blood sugar and lose weight, compared to counting calories.

More Hyperglycemia research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startApril 1, 2022
Project endMarch 31, 2026
Funding year2024
Award (this year)$306,000
NIH project number5R01DK129668-03
Project IDNIH-10825524 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are overweight or obese adults with type 2 diabetes who are currently treated with metformin and have a body mass index (BMI) between 25 and 35.

Less likely to help

Patients who are not overweight or obese, or those who are not currently using metformin for their diabetes management, may not benefit from this research.

What this research studies

This research investigates whether time-restricted eating (TRE) can effectively improve blood sugar levels and aid weight loss in overweight individuals with type 2 diabetes who are only using metformin. Participants will follow a structured eating schedule that limits their daily eating window, allowing them to eat freely within that timeframe. The study will compare the effects of TRE against traditional caloric restriction over a 24-week period, with a focus on understanding how these approaches impact glycemic control and weight management. The study aims to provide a more sustainable dietary option for patients struggling with strict calorie counting.

Why it matters

Potential benefit: If successful, this research could offer a simpler and more effective dietary strategy for managing type 2 diabetes and improving overall health.

How similar studies have gone: Previous research has shown that time-restricted eating can lead to weight loss and improved glycemic measures in individuals without diabetes, but its effects in those with type 2 diabetes are still being explored.

Where this research is happening

  • University of Minnesota
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Chow, Lisa Senye — University of Minnesota
  • Study coordinator: Chow, Lisa Senye

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.