Exploring the roles of proteins in development and disease

Defining multifunctional roles for proteins in development and disease

['FUNDING_OTHER'] · UNIVERSITY OF WYOMING · NIH-10941783

This study is looking at how certain proteins work in both fruit flies and humans to better understand genetic diseases like microcephaly and cancer, with the hope of finding new treatments that could help patients.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF WYOMING (nih funded)
Locations1 site (LARAMIE, UNITED STATES)
Trial IDNIH-10941783 on ClinicalTrials.gov

What this research studies

This research investigates how specific proteins function in both animal development and human health, particularly focusing on their roles in genetic diseases. By using the fruit fly, Drosophila melanogaster, and advanced imaging techniques, the team aims to uncover the secondary functions of proteins that are linked to conditions like microcephaly and cancer. The study will explore how these proteins influence stem cell function and tissue architecture, which is crucial for developing effective therapies. Patients may benefit from insights gained about the genetic causes of diseases and potential new treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals with genetic conditions related to protein functions, such as microcephaly or certain cancers.

Not a fit: Patients with conditions unrelated to protein function or those not affected by genetic diseases may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic approaches for genetic diseases linked to protein dysfunction.

How similar studies have performed: Previous research has shown success in understanding protein functions in model organisms, suggesting that this approach could yield valuable insights.

Where this research is happening

LARAMIE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.