Exploring the role of toxic elements and nanoparticles in ALS development
Investigating Toxic Elements and Nanoparticles in ALS Etiology: A Geospatial and Toxicological Evaluation of Massachusetts ALS Registry Patients
This study is looking into how certain harmful substances in the environment might be linked to the development of ALS, and it’s for people with ALS who can share their experiences and health history to help us understand this connection better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth-Hitchcock Clinic NIH-funded |
| Lab location | 1 site (Lebanon, United States) |
| Project ID | NIH-10897185 on NIH RePORTER |
What this research studies
This research investigates how exposure to toxic elements and nanoparticles may contribute to the development of Amyotrophic Lateral Sclerosis (ALS). By analyzing data from patients registered in the Massachusetts ALS Registry, the study aims to identify environmental factors that could influence the onset of this neurodegenerative disease. The approach includes geospatial evaluations and toxicological assessments to better understand the relationship between these exposures and ALS. Patients may be asked to provide information about their environmental exposures and health history to aid in this investigation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with ALS or those who have a family history of the disease.
Not a fit: Patients with other neurodegenerative diseases unrelated to ALS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of ALS causes and potentially inform prevention strategies.
How similar studies have performed: Previous research has indicated a link between environmental toxins and ALS, suggesting that this approach may yield valuable insights.
Where this research is happening
Lebanon, United States
- Dartmouth-Hitchcock Clinic — Lebanon, United States (Active)
Researchers
- Principal investigator: Stommel, Elijah W — Dartmouth-Hitchcock Clinic
- Study coordinator: Stommel, Elijah W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.