Exploring the role of specific RNA sequences and proteins in Alzheimer's disease
Identifying and understanding the role of repeat RNAs and RAN proteins in Alzheimer's disease
This study is looking at how certain genetic factors and proteins might play a role in Alzheimer's disease, and it invites patients to help by sharing genetic samples or taking part in assessments to help researchers learn more about how these factors relate to memory and thinking changes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11076315 on NIH RePORTER |
What this research studies
This research investigates the potential role of repeat RNAs and RAN proteins in the development and progression of Alzheimer's disease. By examining genetic factors and protein accumulation associated with Alzheimer's, the study aims to uncover new insights into the disease's pathology. Patients may be involved in providing genetic samples or participating in assessments that help researchers understand the relationship between these molecular factors and cognitive decline. The approach combines genetic analysis with clinical evaluations to better understand how these elements contribute to Alzheimer's symptoms.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are experiencing cognitive decline or have a family history of Alzheimer's disease.
Not a fit: Patients under the age of 65 or those without cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic tools or therapeutic strategies for Alzheimer's disease.
How similar studies have performed: Previous research has shown promising results in understanding the genetic factors contributing to neurodegenerative diseases, suggesting that this approach may yield valuable insights.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Nguyen, Lien — University of Florida
- Study coordinator: Nguyen, Lien
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.