Exploring the role of specific genes in amyotrophic lateral sclerosis
Investigating the Role of MS4As in Amyotrophic Lateral Sclerosis
This study is looking at how specific genes might affect the way ALS develops and progresses, and it’s inviting patients to help by sharing samples or participating in activities that could lead to new treatments for this condition.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-10995262 on NIH RePORTER |
What this research studies
This research investigates how certain genes, particularly those in the MS4A family, may influence the development and progression of amyotrophic lateral sclerosis (ALS). By examining the role of these genes in neuroinflammation, the study aims to uncover potential pathways that could lead to new treatments for ALS. Patients may be involved in providing biological samples or participating in assessments that help researchers understand the genetic factors associated with their condition. The approach combines genetic analysis with insights from both human and animal models to identify common mechanisms in neurodegenerative diseases.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals diagnosed with amyotrophic lateral sclerosis, particularly those who are interested in contributing to genetic research.
Not a fit: Patients with neurodegenerative diseases other than ALS or those who do not have a genetic predisposition to the conditions being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for ALS, potentially improving patient outcomes and quality of life.
How similar studies have performed: Previous research has shown promise in understanding the genetic factors of neurodegenerative diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Hiller, Abigail Jean — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Hiller, Abigail Jean
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.