Exploring the role of gut microbiota in Alzheimer's disease using mouse models
Functional Microbiomics Core
['FUNDING_OTHER'] · UNIVERSITY OF LOUISVILLE · NIH-11038015
This study is looking at how the bacteria in our gut might affect inflammation and the progression of Alzheimer's disease, using special mouse models to help researchers learn more about it, which could lead to new treatments that may help patients in the future.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF LOUISVILLE (nih funded) |
| Locations | 1 site (LOUISVILLE, UNITED STATES) |
| Trial ID | NIH-11038015 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how gut microbiota influences inflammation and disease progression in Alzheimer's disease by utilizing specialized mouse models. The Functional Microbiomics Core provides essential resources for researchers, including the ability to culture specific bacteria and analyze their effects on health. By employing advanced sequencing techniques and bioinformatics, the project aims to uncover the complex interactions between microbiota and neurological conditions. Patients may benefit indirectly through advancements in understanding Alzheimer's disease and potential new therapeutic approaches.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are individuals at risk for or diagnosed with Alzheimer's disease.
Not a fit: Patients with non-neurological conditions or those not affected by Alzheimer's disease may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for Alzheimer's disease by targeting gut microbiota.
How similar studies have performed: Previous research has shown promising results in understanding the gut-brain axis and its implications for neurological diseases, indicating that this approach has potential for success.
Where this research is happening
LOUISVILLE, UNITED STATES
- UNIVERSITY OF LOUISVILLE — LOUISVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BODDULURI, HARIBABU — UNIVERSITY OF LOUISVILLE
- Study coordinator: BODDULURI, HARIBABU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease