Exploring the relationship between macromolecular structure and function.
Official title: Oklahoma COBRE in Structural Biology
Funded at University of Oklahoma · NIH-11083727 · Data updated 2026-11-12
This study is all about understanding how the shapes of important molecules in our bodies affect how they work, and it aims to help scientists work together better, which could eventually lead to new treatments for patients.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma NIH-funded |
| Lab location | 1 site (Norman, United States) |
| Project start | June 1, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,141,533 |
| NIH project number | 5P30GM145423-04 |
| Project ID | NIH-11083727 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that are influenced by macromolecular structures, such as genetic disorders or certain cancers.
✕Less likely to help
Patients with conditions unrelated to macromolecular structure or function may not receive direct benefits from this research.
What this research studies
This research focuses on structural biology, which examines how the structure of macromolecules relates to their function. The Oklahoma Center of Biomedical Research Excellence in Structural Biology provides support for faculty research projects and core facilities that specialize in crystallization, protein expression, purification, and biophysical analysis. By enhancing research capabilities and training in structural biology, the project aims to foster collaboration among researchers and improve scientific understanding in this field. Patients may benefit indirectly through advancements in biomedical research that could lead to new treatments.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in understanding diseases at a molecular level, potentially resulting in new therapeutic strategies.
How similar studies have gone: Previous research in structural biology has shown success in elucidating molecular mechanisms and developing targeted therapies, indicating a promising approach.
Where this research is happening
-
University of Oklahoma
Norman, United States Active
Researchers
- Principal investigator: West, Ann H — University of Oklahoma
- Study coordinator: West, Ann H
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.