NIH-funded research R01 grant

Exploring the links between genetics and mental health in people with PTSD and alcohol use issues

Official title: Integrating genetic and ecological momentary assessment technologies to advance models of PTSD-AUD comorbidity

Funded at Virginia Commonwealth University · NIH-10909352 · Data updated 2026-11-12

This study is looking at how PTSD and alcohol use problems affect each other in people living in cities who may be struggling financially, and it aims to find better ways to help those who are dealing with both issues.

More PTSD research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University
NIH-funded
Lab location1 site (Richmond, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$675,500
NIH project number5R01AA030549-02
Project IDNIH-10909352 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals from urban, low socioeconomic backgrounds who experience both PTSD and alcohol use disorder.

Less likely to help

Patients who do not have PTSD or alcohol use disorder may not benefit from this research.

What this research studies

This research investigates the relationship between posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD), particularly in urban populations with low socioeconomic status. By integrating genetic data with ecological momentary assessment technologies, the study aims to understand how these two conditions influence each other over time. Participants will be recruited from the Grady Trauma Project and will provide data through a series of assessments to identify patterns and potential genetic factors involved in their comorbidity. The goal is to fill existing gaps in knowledge and improve treatment strategies for affected individuals.

Why it matters

Potential benefit: If successful, this research could lead to more effective interventions tailored to individuals suffering from both PTSD and AUD.

How similar studies have gone: Previous research has shown promising results in understanding the comorbidity of PTSD and AUD, but this approach is novel in its integration of genetic and ecological momentary assessment methods.

Where this research is happening

  • Virginia Commonwealth University
    Richmond, United States
    Active

Researchers

  • Principal investigator: Amstadter, Ananda B — Virginia Commonwealth University
  • Study coordinator: Amstadter, Ananda B

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.