Exploring the links between emotions, inflammation, and pain in Veterans with Fibromyalgia.
Official title: Relationships of affect and neuroinflammation with clinical pain in Veterans with Fibromyalgia.
Funded at Birmingham VA Medical Center · NIH-11000049 · Data updated 2026-11-12
This study is looking at how feelings and inflammation can impact pain in Veterans with Fibromyalgia, and it aims to create a special exercise program to help improve their well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Birmingham VA Medical Center NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | October 1, 2024 |
| Project end | September 30, 2026 |
| Funding year | 2025 |
| NIH project number | 1IK1RX004807-01A2 |
| Project ID | NIH-11000049 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Veterans diagnosed with Fibromyalgia, particularly those experiencing significant emotional distress related to their condition.
✕Less likely to help
Patients who do not have Fibromyalgia or those with other unrelated chronic pain conditions may not benefit from this research.
What this research studies
This research investigates how emotional states and neuroinflammation affect pain levels in Veterans suffering from Fibromyalgia (FM). It aims to understand the relationship between positive and negative emotions and pain experiences, while also examining the role of inflammation in these processes. The study will involve Veterans with FM and those without, focusing on their emotional traits and how these may influence their pain management. Additionally, the research seeks to develop an exercise program tailored to the needs of Veterans with FM to enhance their overall well-being.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies and emotional support for Veterans with Fibromyalgia.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between emotional health and chronic pain, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Birmingham VA Medical Center
Birmingham, United States Active
Researchers
- Principal investigator: Taylor, Taylor L — Birmingham VA Medical Center
- Study coordinator: Taylor, Taylor L
Related research
Other NIH-funded projects on the same topics.
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Noninvasive deep brain stimulation for fibromyalgia relief
A noninvasive ultrasound approach aims to directly modulate deep brain pain circuits to help people with fibromyalgia who don’t respond well to current treatments.
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LARKSPUR-mHealth: a remote positive-emotion program for fibromyalgia
A nationwide, fully online program tests whether brief daily skills to boost positive emotions can ease pain and improve daily life for adults with fibromyalgia.
-
Biomarker-Guided Fibromyalgia Treatment with Non-Invasive Vagus Nerve Stimulation
A study to see if non-invasive vagus nerve stimulation can help people with fibromyalgia by balancing gut health and identifying biomarkers to guide treatment.
-
Auricular nerve stimulation for fibromyalgia in veterans
Aurasicular nerve stimulation therapy is being tested in veterans with fibromyalgia to see if it reduces pain and improves function compared to a sham treatment.
-
Ear nerve stimulation for veterans with fibromyalgia
This tests whether a small electrical device placed on the ear can reduce pain and improve daily function for veterans with fibromyalgia.
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Relationships among mood, inflammation, and pain in Veterans with fibromyalgia
This project explores how feelings, brain inflammation, and pain relate in Veterans living with fibromyalgia and how exercise might help.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.