Exploring the link between social isolation and depression during the COVID-19 pandemic.

Depression, Isolation, and Social Connectivity Online (DISCO)

NIH-funded research Massachusetts General Hospital · NIH-10612642

This study looks at how feeling lonely during the COVID-19 pandemic has affected depression rates, especially in communities that need extra support, and it wants to find out how changes in our social connections and online interactions might help improve mental health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10612642 on NIH RePORTER

What this research studies

This research investigates how social isolation, exacerbated by the COVID-19 pandemic, affects rates of major depression, particularly in vulnerable communities. It aims to understand which aspects of social networks have been most disrupted and how online social behaviors may influence mental health outcomes. By analyzing data from a large-scale survey conducted across the United States, the study seeks to identify potential intervention targets to mitigate the impact of social disconnection on depression.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults aged 21 and older, especially those from vulnerable or underserved communities experiencing social isolation.

Not a fit: Patients who are not experiencing social isolation or who do not have symptoms of depression may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for reducing depression in socially isolated individuals, particularly in underserved communities.

How similar studies have performed: Other research has shown that understanding social connectivity can significantly impact mental health outcomes, indicating that this approach has potential for success.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.