Exploring the link between physical frailty and cognitive impairment in older adults
Concurrent trajectories of physical frailty and cognitive impairment among nursing home residents and community-dwelling older adults
This study is looking at how physical weakness and memory problems often happen together in older adults, especially those living in nursing homes or in the community, to better understand how these issues affect each other and how depression might play a role, with the goal of finding ways to help those who are most at risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-10898069 on NIH RePORTER |
What this research studies
This research investigates how physical frailty and cognitive impairment coexist among older adults, particularly focusing on those in nursing homes and community settings. It aims to understand the prevalence of these conditions and their complex interactions, including how they may influence each other and the role of depression in this relationship. By utilizing longitudinal data and advanced statistical methods, the study seeks to identify subgroups of older adults who may be at higher risk for these issues, ultimately aiming to improve management strategies for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above, particularly those living in nursing homes or community-dwelling settings who may be experiencing physical frailty or cognitive impairment.
Not a fit: Patients under 65 years old or those without any signs of physical frailty or cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of frailty and cognitive impairment, improving the quality of life for older adults.
How similar studies have performed: Previous research has shown that understanding the interplay between physical frailty and cognitive impairment can lead to significant advancements in care strategies, indicating that this approach has potential for success.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Yuan, Yiyang — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Yuan, Yiyang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.