Exploring the link between pain, nutrition, and Alzheimer's disease
Official title: Pain and Nutrition in Dementia and Alzheimer's-2 (PANDA-2)
Funded at University of Florida · NIH-11143990 · Data updated 2026-11-12
This study is looking at how chronic pain and certain vitamins, like A and D, might affect the development of Alzheimer's disease and similar conditions in older adults, and it hopes to find ways to improve treatment and prevention by understanding how diet and pain are connected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | August 15, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $249,000 |
| NIH project number | 4R00AG081552-02 |
| Project ID | NIH-11143990 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include older adults who are experiencing chronic pain and may have Alzheimer's disease or related dementias.
✕Less likely to help
Patients who are not experiencing chronic pain or do not have Alzheimer's disease or related dementias may not benefit from this research.
What this research studies
This research investigates how chronic pain and nutritional factors, particularly vitamins A and D, may influence the development and progression of Alzheimer's disease and related dementias. By examining the epigenetic changes associated with diet and pain modulation in older adults, the study aims to uncover shared mechanisms that could lead to better treatment and prevention strategies. Participants may be asked about their dietary habits and pain experiences to help identify patterns that could inform future interventions.
Why it matters
Potential benefit: If successful, this research could lead to improved dietary recommendations and treatments for individuals suffering from Alzheimer's disease and chronic pain.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between nutrition and chronic pain, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Strath, Larissa J — University of Florida
- Study coordinator: Strath, Larissa J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.