Exploring the link between pain, nutrition, and Alzheimer's disease

Pain and Nutrition in Dementia and Alzheimer's-2 (PANDA-2)

NIH-funded research University of Florida · NIH-11143990

This study is looking at how chronic pain and certain vitamins, like A and D, might affect the development of Alzheimer's disease and similar conditions in older adults, and it hopes to find ways to improve treatment and prevention by understanding how diet and pain are connected.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11143990 on NIH RePORTER

What this research studies

This research investigates how chronic pain and nutritional factors, particularly vitamins A and D, may influence the development and progression of Alzheimer's disease and related dementias. By examining the epigenetic changes associated with diet and pain modulation in older adults, the study aims to uncover shared mechanisms that could lead to better treatment and prevention strategies. Participants may be asked about their dietary habits and pain experiences to help identify patterns that could inform future interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults who are experiencing chronic pain and may have Alzheimer's disease or related dementias.

Not a fit: Patients who are not experiencing chronic pain or do not have Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved dietary recommendations and treatments for individuals suffering from Alzheimer's disease and chronic pain.

How similar studies have performed: Previous research has shown promising results in understanding the relationship between nutrition and chronic pain, suggesting that this approach may yield valuable insights.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.