NIH-funded research NIH-funded research

Exploring the link between obsessive-compulsive personality traits and suicide risk in veterans

Official title: Pathways to Hope: Pilot fMRI Study of OCPD and Suicide Risk in Trauma-Exposed Veterans

Funded at Providence VA Medical Center · NIH-11077315 · Data updated 2026-11-12

This study is looking at how certain personality traits in veterans, especially those related to obsessive-compulsive behavior, can affect their risk of suicide and emotional struggles, and it aims to find better ways to help them feel better through brain scans and therapy.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionProvidence VA Medical Center
NIH-funded
Lab location1 site (Providence, United States)
Project startApril 1, 2024
Project endMarch 31, 2026
Funding year2025
NIH project number5I21RX005150-02
Project IDNIH-11077315 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are veterans who exhibit traits of obsessive-compulsive personality disorder and have experienced trauma.

Less likely to help

Patients who do not have obsessive-compulsive personality traits or who are not veterans may not benefit from this research.

What this research studies

This research investigates how obsessive-compulsive personality traits, particularly in veterans, relate to suicide risk and emotional challenges. By using functional MRI (fMRI), the study aims to understand the brain mechanisms behind these traits and their impact on interpersonal relationships and mental health. The goal is to develop better treatment strategies that combine neuromodulation with psychotherapy to support veterans facing these issues. Participants will be monitored over time to assess changes in their functioning and emotional well-being.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options that enhance the quality of life and reduce suicide risk among veterans with obsessive-compulsive personality traits.

How similar studies have gone: Previous research has shown promise in using neuromodulation techniques to enhance psychotherapy outcomes, suggesting potential success for this approach.

Where this research is happening

  • Providence VA Medical Center
    Providence, United States
    Active

Researchers

  • Principal investigator: Barredo, Jennifer Leigh — Providence VA Medical Center
  • Study coordinator: Barredo, Jennifer Leigh

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.