NIH-funded research Career grant

Exploring the link between high blood pressure and uterine fibroids in women

Official title: Hypertension, antihypertensive treatment, and uterine fibroid diagnosis in an integrated healthcare system

Funded at Kaiser Foundation Research Institute · NIH-11054085 · Data updated 2026-11-12

This study is looking at how high blood pressure and blood pressure medications might affect the growth of uterine fibroids in women between 18 and 55, to help find better ways to understand and treat this condition.

More Hypertension research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute
NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project startMarch 4, 2025
Project endFebruary 28, 2029
Funding year2025
Award (this year)$178,068
NIH project number1K01HL173652-01A1
Project IDNIH-11054085 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women aged 18-55 who have been diagnosed with hypertension or are using antihypertensive medications.

Less likely to help

Patients who do not have high blood pressure or uterine fibroids may not benefit from this research.

What this research studies

This research investigates how high blood pressure and the use of antihypertensive medications may influence the development of uterine fibroids in women aged 18-55. By analyzing electronic health records, the study aims to identify patterns in blood pressure changes and their relationship to fibroid diagnosis. The research will also explore the role of the renin-angiotensin system, a hormonal system that regulates blood pressure, in the development of fibroids. This could lead to a better understanding of the underlying causes of fibroids and potential new treatment options.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for women suffering from uterine fibroids, potentially reducing symptoms and enhancing quality of life.

How similar studies have gone: Preliminary evidence suggests a link between blood pressure and fibroid development, indicating that this research builds on existing findings but explores a relatively novel approach.

Where this research is happening

  • Kaiser Foundation Research Institute
    Oakland, United States
    Active

Researchers

  • Principal investigator: Mitro, Susanna Decker — Kaiser Foundation Research Institute
  • Study coordinator: Mitro, Susanna Decker

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.