Exploring the link between gut bacteria and cognitive decline in Latinos

Microbiome Multi-Omics and Cognitive Decline in Latinos

NIH-funded research University of Massachusetts Lowell · NIH-10661289

This study is looking at how the bacteria in your gut might affect brain health, especially for Puerto Ricans who are more likely to experience Alzheimer's disease, to help us understand how to keep our minds sharp as we age.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Massachusetts Lowell NIH-funded
Lab location1 site (Lowell, United States)
Project IDNIH-10661289 on NIH RePORTER

What this research studies

This research investigates how the gut microbiome may influence cognitive decline, particularly in Puerto Ricans who are at a higher risk for Alzheimer's disease. By studying a large group of participants from the Boston Puerto Rican Health Study, the project aims to understand the relationship between gut health and brain function. The research will utilize advanced multi-omics techniques to analyze biological data and cognitive assessments over time, providing insights into how gut bacteria may affect cognitive health. This study is significant as it focuses on a minority population that has been underrepresented in similar research.

Who could benefit from this research

Good fit: Ideal candidates for this research are Puerto Rican adults aged 21 and older who are at risk for Alzheimer's disease.

Not a fit: Patients who are not of Latino descent or those without risk factors for cognitive decline may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing or mitigating cognitive decline in Latino populations.

How similar studies have performed: While research on the gut-brain connection is emerging, this specific focus on Puerto Ricans and cognitive decline is novel and has not been extensively studied before.

Where this research is happening

Lowell, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.