Exploring the link between gum disease and HIV treatment
Periodontitis as a comorbidity in SIV infection and Antiretroviral Therapy
This study is looking at how gum disease affects people with HIV and how their treatment might change the bacteria in their mouths and their immune system, helping us understand the links between oral health and overall well-being for those living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-10892166 on NIH RePORTER |
What this research studies
This research investigates how periodontitis, a serious gum disease, interacts with HIV-1 infection and the effects of antiretroviral therapy (ART). It aims to understand the changes in oral bacteria and immune responses in patients with HIV and how these factors contribute to gum disease. By analyzing the oral microbiome and immune system dynamics, the study seeks to uncover the connections between chronic oral infections and overall health in individuals living with HIV. This multi-disciplinary approach involves collaboration across institutions to gather comprehensive data.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living with HIV who are undergoing antiretroviral therapy and may be experiencing oral health issues.
Not a fit: Patients who do not have HIV or those without any signs of gum disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved oral health management strategies for patients with HIV, potentially reducing the severity of periodontitis.
How similar studies have performed: Previous research has shown significant interactions between oral health and systemic diseases, but this specific investigation into HIV and periodontitis is relatively novel.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Datta, Prasun K — Tulane University of Louisiana
- Study coordinator: Datta, Prasun K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.