Exploring the immune environment in tumors that don't respond to treatment
Official title: Multiplex imaging in therapy refractory tumors: understanding the spatiotemporal facets of an immunosuppressive environment
Funded at University of California, San Diego · NIH-11130388 · Data updated 2026-11-12
This study is looking at how immune cells behave around tumors that don't respond to treatment, hoping to find new ways to help patients with tough-to-treat cancers.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | August 1, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $249,000 |
| NIH project number | 4R00GM147841-02 |
| Project ID | NIH-11130388 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with therapy-refractory tumors who have not responded to standard cancer treatments.
✕Less likely to help
Patients with tumors that are responsive to current therapies may not receive direct benefits from this research.
What this research studies
This research investigates the complex immune environment surrounding tumors that are resistant to therapy. By using advanced imaging techniques, the study aims to visualize and understand how immune cells interact within these tumors over time. Patients may benefit from insights that could lead to more effective treatment strategies for therapy-resistant cancers. The research focuses on identifying specific immune factors that contribute to tumor growth and survival despite treatment efforts.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches that enhance the effectiveness of cancer treatments for patients with resistant tumors.
How similar studies have gone: Other research has shown promising results using similar imaging techniques to study tumor environments, indicating potential for success in this approach.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Maltez, Vivien Ileana — University of California, San Diego
- Study coordinator: Maltez, Vivien Ileana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.