Exploring the hidden abilities of fungi to produce new medicines
Official title: Accessing the hidden biosynthetic capabilities of fungi
Funded at University of Wisconsin-Madison · NIH-11006013 · Data updated 2026-11-12
This study is looking at how certain fungi can create new natural substances that might help develop new medicines for fighting infections and lowering cholesterol, which could lead to better treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $495,117 |
| NIH project number | 1R35GM156119-01 |
| Project ID | NIH-11006013 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with bacterial infections or high cholesterol levels.
✕Less likely to help
Patients who are not affected by bacterial infections or do not have issues related to cholesterol may not receive any benefit from this research.
What this research studies
This research investigates the untapped potential of filamentous fungi to produce new natural products that could lead to novel antibacterial and cholesterol-lowering drugs. By developing advanced bioinformatics tools, the project aims to identify unique chemical compounds produced by fungi that have not been previously characterized. The research will also explore how environmental factors, such as metal concentrations, influence the production of these compounds. Patients may benefit from new treatments derived from these discoveries.
Why it matters
Potential benefit: If successful, this research could lead to the development of new medications for bacterial infections and cholesterol management.
How similar studies have gone: Other research has shown promise in discovering new natural products from fungi, indicating that this approach could yield significant results.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Keller, Nancy P — University of Wisconsin-Madison
- Study coordinator: Keller, Nancy P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.