Exploring the genetics of aging and behavior in diverse populations
Official title: Studying the Genetics of Aging, Behavioral, and Social Phenotypes in Diverse Populations
Funded at University of Southern California · NIH-11089596 · Data updated 2026-11-12
This study is looking at how our genes affect aging and behavior in different groups of people, and it's creating new tools to help researchers better understand genetic data, making it easier for everyone to work together and learn more about our health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | May 15, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $614,996 |
| NIH project number | 5R01AG081518-03 |
| Project ID | NIH-11089596 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals from diverse ethnic backgrounds who are interested in the genetic factors influencing aging and behavior.
✕Less likely to help
Patients who do not have an interest in genetic research or who belong to populations that are not represented in the study may not benefit from this research.
What this research studies
This research focuses on understanding how genetics influences aging and behavioral traits across different populations. It aims to develop innovative tools that enhance genetic research by allowing for the analysis of diverse genetic data without the bias of homogeneous ancestry. By creating the Genetic-Related-Matrix-Matched Association study (GRMMA) tool and the SBayes-Universal (SBayesU) tool, the project seeks to improve the accuracy of genome-wide association studies (GWAS) and polygenic scores. These tools will be made publicly available to facilitate broader research and collaboration.
Why it matters
Potential benefit: If successful, this research could lead to more accurate genetic insights that improve understanding and treatment of aging-related conditions like Alzheimer's disease.
How similar studies have gone: Previous research has shown success in using similar genetic analysis tools, indicating a promising approach to understanding complex traits in diverse populations.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Turley, Patrick Ansel — University of Southern California
- Study coordinator: Turley, Patrick Ansel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.