Exploring the genetics of aging and behavior in diverse populations

Studying the Genetics of Aging, Behavioral, and Social Phenotypes in Diverse Populations

NIH-funded research University of Southern California · NIH-11089596

This study is looking at how our genes affect aging and behavior in different groups of people, and it's creating new tools to help researchers better understand genetic data, making it easier for everyone to work together and learn more about our health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-11089596 on NIH RePORTER

What this research studies

This research focuses on understanding how genetics influences aging and behavioral traits across different populations. It aims to develop innovative tools that enhance genetic research by allowing for the analysis of diverse genetic data without the bias of homogeneous ancestry. By creating the Genetic-Related-Matrix-Matched Association study (GRMMA) tool and the SBayes-Universal (SBayesU) tool, the project seeks to improve the accuracy of genome-wide association studies (GWAS) and polygenic scores. These tools will be made publicly available to facilitate broader research and collaboration.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals from diverse ethnic backgrounds who are interested in the genetic factors influencing aging and behavior.

Not a fit: Patients who do not have an interest in genetic research or who belong to populations that are not represented in the study may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate genetic insights that improve understanding and treatment of aging-related conditions like Alzheimer's disease.

How similar studies have performed: Previous research has shown success in using similar genetic analysis tools, indicating a promising approach to understanding complex traits in diverse populations.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.