Exploring the genetic links between PTSD and alcohol use disorder.
Genetic relationships between PTSD and Alcohol Use Disorder: Integrating GWAS and Deeply Phenotyped Longitudinal data.
This study is looking at how experiences of childhood trauma, like violence, can lead to problems with drinking and anxiety later in life, especially for those with a family history of these issues, and it aims to understand the genetic links and brain changes involved.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Suny Downstate Medical Center NIH-funded |
| Lab location | 1 site (Brooklyn, United States) |
| Project ID | NIH-10898022 on NIH RePORTER |
What this research studies
This research investigates how childhood trauma, particularly interpersonal violence, influences the development of alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) across a person's life. By analyzing genetic data and longitudinal information, the study aims to uncover the shared genetic risks and mechanisms that contribute to the co-occurrence of these conditions. The research focuses on understanding how trauma affects brain development and increases the likelihood of developing AUD and PTSD, especially in individuals with a family history of these disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of childhood trauma, particularly those who have experienced interpersonal violence.
Not a fit: Patients who have not experienced childhood trauma or do not have a family history of AUD or PTSD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for individuals at risk of developing AUD and PTSD.
How similar studies have performed: While there is preliminary evidence linking childhood trauma to AUD and PTSD, this research is novel in its longitudinal approach and comprehensive examination of genetic factors.
Where this research is happening
Brooklyn, United States
- Suny Downstate Medical Center — Brooklyn, United States (Active)
Researchers
- Principal investigator: Meyers, Jacquelyn Leigh — Suny Downstate Medical Center
- Study coordinator: Meyers, Jacquelyn Leigh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.