Exploring the genetic links between cannabis use and schizophrenia
Identifying genetic sources of comorbidity between cannabis and schizophrenia using genome-wide and integrative omics data
This study is looking at how certain genes might link cannabis use disorder with schizophrenia, aiming to help us understand who might be at greater risk and how we can better support those individuals.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11051201 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that may connect cannabis use disorder (CUD) with schizophrenia. By analyzing large datasets from genome-wide association studies (GWAS), the project aims to identify genetic variants that contribute to both conditions. The goal is to understand how these genetic influences may lead to increased risk for individuals, particularly among vulnerable populations. This research could help in identifying specific subgroups at higher risk and inform future prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of cannabis use and those diagnosed with schizophrenia or related psychiatric disorders.
Not a fit: Patients who do not use cannabis or do not have any psychiatric disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of the risks associated with cannabis use in relation to schizophrenia.
How similar studies have performed: Previous research has shown promising results in understanding the genetic correlations between substance use disorders and psychiatric conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Johnson, Emma Covey — Washington University
- Study coordinator: Johnson, Emma Covey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.