Exploring the genetic factors behind cerebral palsy
Investigating the Genetic Landscape of Cerebral Palsy
This study is looking into the genetic reasons behind cerebral palsy, especially in cases where the cause isn't obvious, and it's for families of children with CP who want to help researchers find out more about the condition and improve care options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11080905 on NIH RePORTER |
What this research studies
This research investigates the genetic causes of cerebral palsy (CP), particularly focusing on cases where no clear risk factors are identified, known as cryptogenic CP. By analyzing the genetic data of a large group of children with CP, the study aims to identify specific gene variants that may contribute to the condition. Participants will undergo detailed clinical assessments and exome sequencing to uncover potential genetic links. The goal is to enhance understanding of CP and improve diagnostic and treatment options for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years diagnosed with cerebral palsy, particularly those with cryptogenic CP.
Not a fit: Patients with cerebral palsy who have well-defined perinatal risk factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnosis and targeted treatments for children with cerebral palsy.
How similar studies have performed: Previous research has shown promise in identifying genetic factors in rare cases of cerebral palsy, but this study aims to expand on those findings with a larger cohort.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Srivastava, Siddharth — Boston Children's Hospital
- Study coordinator: Srivastava, Siddharth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.