Exploring the effects of sleep loss in a mouse model of autism
Official title: UNDERSTANDING THE CONSEQUENCES OF SLEEP LOSS IN AN AUTISM MOUSE MODEL
Funded at Washington State University · NIH-10930977 · Data updated 2026-11-12
This study looks at how not getting enough sleep affects behavior and brain function in young mice that have a genetic link to autism, hoping to learn more about the sleep challenges faced by people with autism.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington State University NIH-funded |
| Lab location | 1 site (Pullman, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $49,974 |
| NIH project number | 5F99NS135815-02 |
| Project ID | NIH-10930977 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with autism spectrum disorder who experience sleep disturbances.
✕Less likely to help
Patients without autism spectrum disorder or those who do not experience sleep problems may not benefit from this research.
What this research studies
This research investigates how sleep deprivation affects behavior and brain function in a specific mouse model of autism spectrum disorder (ASD). By studying young mice with a genetic mutation linked to ASD, the researchers aim to uncover the molecular changes that occur due to lack of sleep. The study utilizes advanced techniques like polysomnography to monitor sleep patterns and assess behavioral outcomes. Understanding these effects could provide insights into the challenges faced by individuals with ASD related to sleep.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of sleep-related issues in individuals with autism, potentially improving their quality of life.
How similar studies have gone: Previous studies have shown that understanding sleep issues in animal models can lead to significant insights into human conditions, suggesting this approach may yield valuable results.
Where this research is happening
-
Washington State University
Pullman, United States Active
Researchers
- Principal investigator: Medina, Elizabeth — Washington State University
- Study coordinator: Medina, Elizabeth
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.