Exploring the diversity and function of bacteriophages to combat antibiotic resistance
Bacteriophage diversity, dynamics, function, and exploitation
This study is exploring how certain viruses that attack bacteria, called bacteriophages, can help us find new ways to treat infections, especially those that are hard to cure because they're resistant to antibiotics, so patients might get better options for their treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11074540 on NIH RePORTER |
What this research studies
This research investigates the vast diversity and dynamics of bacteriophages, which are viruses that infect bacteria. By understanding how these phages interact with bacteria, especially in the context of antibiotic resistance, the research aims to uncover new therapeutic strategies to treat bacterial infections. The approach involves analyzing the genetic makeup of various phages and their effects on bacterial cells, which could lead to innovative treatments for infections that are currently difficult to manage. Patients may benefit from new therapies derived from this research that utilize bacteriophages to target antibiotic-resistant bacteria.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals suffering from antibiotic-resistant bacterial infections.
Not a fit: Patients with infections that are easily treatable with existing antibiotics may not receive significant benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for bacterial infections that are resistant to current antibiotics.
How similar studies have performed: Previous research has shown promise in using bacteriophages as a treatment for antibiotic-resistant infections, indicating that this approach has potential for success.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Hatfull, Graham F. — University of Pittsburgh at Pittsburgh
- Study coordinator: Hatfull, Graham F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.