NIH-funded research R01 grant

Exploring the connections between violence, substance use, sleep issues, and high blood pressure in women with HIV.

Official title: Violence, substance use, sleep disturbances, and hypertension among women with HIV: A syndemic approach (VS2H2 Syndemic)

Funded at New York University School of Medicine · NIH-10889239 · Data updated 2026-11-12

This study is looking at how issues like violence, substance use, mental health, and sleep problems come together and affect women living with HIV, to better understand their impact on high blood pressure and sleep issues over time.

More Hypertension research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 15, 2021
Project endJuly 31, 2025
Funding year2024
Award (this year)$634,531
NIH project number5R01HL160324-04
Project IDNIH-10889239 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women living with HIV who may also be experiencing issues related to violence, substance use, sleep disturbances, or hypertension.

Less likely to help

Patients who are not women or who do not have HIV may not receive any benefit from this research.

What this research studies

This research investigates how factors like gender-based violence, substance use, mental health disorders, and sleep disturbances cluster together and affect women living with HIV. By using a syndemic approach, the study aims to understand the interactions between these issues and their impact on hypertension and sleep problems over time. The research will utilize data from the Women's Interagency HIV Study, which focuses on women at risk for or living with HIV in the U.S., to explore these complex relationships. The goal is to provide a comprehensive understanding of how these factors contribute to health outcomes in this vulnerable population.

Why it matters

Potential benefit: If successful, this research could lead to improved health interventions and support for women with HIV, addressing both their mental and physical health needs.

How similar studies have gone: Previous studies have shown success in understanding the syndemic relationships among substance use, violence, and HIV, but this specific approach to hypertension and sleep disturbances in women with HIV is relatively novel.

Where this research is happening

  • New York University School of Medicine
    New York, United States
    Active

Researchers

  • Principal investigator: Lim, Sahnah — New York University School of Medicine
  • Study coordinator: Lim, Sahnah

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.