Exploring the connections between gut microbiota and Alzheimer's disease.
Omics and Technology Core
This study is looking at how the bacteria in our gut might affect Alzheimer's disease by examining samples from participants, and it’s designed for anyone interested in understanding more about how these tiny organisms could play a role in the disease's development.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10693921 on NIH RePORTER |
What this research studies
This research focuses on understanding how the gut microbiome may influence Alzheimer's disease by analyzing high-quality genomic, metabolomic, and imaging data. It aims to integrate this data with clinical information to provide insights into the disease's progression. The project will utilize advanced techniques, including metagenomic sequencing, to profile the microbial communities in fecal samples from participants. By collaborating with leading experts and utilizing standardized procedures, the research seeks to ensure accurate and comprehensive data analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or those at risk of developing it.
Not a fit: Patients with other forms of dementia unrelated to Alzheimer's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into Alzheimer's disease and potential therapeutic strategies targeting the gut microbiome.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between gut microbiota and neurological conditions, indicating potential for success in this area.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Kaddurah-Daouk, Rima F — Duke University
- Study coordinator: Kaddurah-Daouk, Rima F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.