Exploring the connection between stroke and Alzheimer's disease through cellular mechanisms
Dissecting the Molecular Link Between Stroke, Actin, and Alzheimer's Disease
This study is looking at how having a stroke might raise the chances of getting Alzheimer's disease by exploring changes in brain cells, and it hopes to find new ways to help prevent or treat Alzheimer's for people who have had a stroke.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rhode Island NIH-funded |
| Lab location | 1 site (Kingston, United States) |
| Project ID | NIH-10772704 on NIH RePORTER |
What this research studies
This research investigates how stroke may increase the risk of developing Alzheimer's disease by examining the molecular changes that occur in neurons after a stroke. It focuses on the role of the actin cytoskeleton and how its alterations can affect neuronal health and survival. By understanding these cellular processes, the research aims to uncover the long-term impacts of stroke on brain function and the development of neurodegenerative diseases. Patients may benefit from insights that could lead to new therapeutic strategies for preventing or treating Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who have suffered a stroke and are at risk for developing Alzheimer's disease.
Not a fit: Patients who have not experienced a stroke or do not have risk factors for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new ways to prevent or treat Alzheimer's disease in patients who have experienced a stroke.
How similar studies have performed: Previous research has shown promising results in understanding the links between stroke and neurodegenerative diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Kingston, United States
- University of Rhode Island — Kingston, United States (Active)
Researchers
- Principal investigator: Fallini, Claudia — University of Rhode Island
- Study coordinator: Fallini, Claudia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.