Exploring the connection between oral health and mental health in adolescents with HIV

Uncovering the Biological Link between Oral and Mental health in Adolescents Living with HIV (uBLOoM)

NIH-funded research University of Pennsylvania · NIH-11141404

This study looks at how oral health and mental health are connected for teenagers living with HIV, especially those on treatment, to find ways to help them feel better overall.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11141404 on NIH RePORTER

What this research studies

This research investigates how oral health and mental health are interconnected in adolescents living with HIV. It focuses on understanding the biological and immunological mechanisms that may link these two aspects of health, particularly in the context of those receiving antiretroviral therapy. By examining the role of oral microbiota and inflammation, the study aims to uncover potential interventions that could improve overall health outcomes for these adolescents.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents who are living with HIV and receiving antiretroviral therapy.

Not a fit: Patients who are not living with HIV or who are not adolescents may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health interventions that enhance both oral and mental health for adolescents living with HIV.

How similar studies have performed: Other research has shown promising results in understanding the links between oral health and systemic conditions, suggesting that this approach could yield valuable insights.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.