Exploring the connection between cancer and infertility in women
Dissecting the molecular link between cancer and oocyte-based infertility - a pilot study
This study is looking at how a specific protein might connect cancer and infertility in women, aiming to understand why women who have trouble getting pregnant may also face a higher risk of cancer, using a special yeast model to explore these links.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern Mississippi NIH-funded |
| Lab location | 1 site (Hattiesburg, United States) |
| Project ID | NIH-11037520 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms that may link cancer and female infertility, particularly focusing on the role of a protein called Protein Phosphatase 1 (PP1). The study aims to understand how abnormalities in cell cycle regulation can lead to both conditions, as women who struggle with infertility are at a higher risk of developing cancer. By using a humanized yeast model, researchers will test the effects of genetic variations on these processes. This approach allows for high-throughput screening of potential links between cancer-related genetic changes and infertility.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing infertility, particularly those with a history of cancer or at risk for developing cancer.
Not a fit: Patients who are not experiencing infertility or have no family history of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the causes of infertility and cancer, potentially improving prevention and treatment strategies for affected women.
How similar studies have performed: While the specific molecular link between cancer and infertility is still being explored, similar research approaches have shown promise in understanding complex disease mechanisms.
Where this research is happening
Hattiesburg, United States
- University of Southern Mississippi — Hattiesburg, United States (Active)
Researchers
- Principal investigator: Camlin, Nicole Jacqueline — University of Southern Mississippi
- Study coordinator: Camlin, Nicole Jacqueline
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.