Exploring the connection between aging eyes and Alzheimer's disease
Aging eyes and aging brains in studying alzheimer's disease: Modern ophthalmic data collection in the adult changes in thought (ACT) study
This study is looking at how changes in the eyes might be connected to Alzheimer's and similar conditions, and it's for older adults, especially those from diverse backgrounds, to help us learn more about how our brains age.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10976376 on NIH RePORTER |
What this research studies
This research investigates how changes in the eyes may relate to Alzheimer's disease and related dementias. By collecting detailed, non-invasive visual function and retinal imaging data, the study aims to enhance our understanding of aging brains. It utilizes a large cohort of older adults who have been followed for decades, allowing researchers to analyze both new and existing eye clinical data. The study also emphasizes diversity by targeting racial and ethnic minorities in its recruitment efforts.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those who are dementia-free and may be at risk for Alzheimer's disease.
Not a fit: Patients with advanced Alzheimer's disease or those who do not have any eye health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and understanding of Alzheimer's disease through eye health.
How similar studies have performed: Previous research has shown promising results in linking eye health to cognitive decline, suggesting that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Lee, Cecilia Sungmin — University of Washington
- Study coordinator: Lee, Cecilia Sungmin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.