Exploring the chemical changes in the brain related to Alzheimer's disease
High-Throughput 3D Multiscale Mass Spectrometry Imaging for Understanding Neurochemical Heterogeneity in Alzheimer's Disease
['FUNDING_R01'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-11091579
This study is looking at how Alzheimer's disease changes the brain's chemistry using special imaging technology, which could help us understand the disease better and find new ways to help those affected.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded) |
| Locations | 1 site (CHAMPAIGN, UNITED STATES) |
| Trial ID | NIH-11091579 on ClinicalTrials.gov |
What this research studies
This research investigates the biochemical changes in the brain associated with Alzheimer's disease (AD) using advanced imaging techniques. By employing high-throughput 3D mass spectrometry imaging, the study aims to map and analyze the molecular profiles of brain tissues affected by AD. This approach allows researchers to understand the neurochemical heterogeneity and identify specific alterations in vulnerable brain regions, which could lead to better insights into the disease's progression and potential interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those exhibiting early signs of cognitive decline.
Not a fit: Patients with other forms of dementia unrelated to Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for Alzheimer's disease.
How similar studies have performed: Previous research using mass spectrometry imaging has shown promise in understanding neurodegenerative diseases, indicating potential success for this novel approach.
Where this research is happening
CHAMPAIGN, UNITED STATES
- UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN — CHAMPAIGN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAM, FAN — UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
- Study coordinator: LAM, FAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome