Exploring the causes of early COPD
Understanding the Origins of Early COPD
['FUNDING_R01'] · UNIV OF MASSACHUSETTS MED SCH WORCESTER · NIH-11180772
This study is looking at the early changes in the lungs that can lead to COPD, using advanced imaging to find out who might be at risk for more serious problems, and it’s for anyone who wants to help us understand how to stop COPD from getting worse.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MASSACHUSETTS MED SCH WORCESTER (nih funded) |
| Locations | 1 site (WORCESTER, UNITED STATES) |
| Trial ID | NIH-11180772 on ClinicalTrials.gov |
What this research studies
This research investigates the early biological processes that lead to Chronic Obstructive Pulmonary Disease (COPD), focusing on small airway abnormalities that can be detected through advanced imaging techniques. By analyzing immune responses and airway surface liquid, the study aims to identify individuals at risk of developing more severe forms of the disease. Participants will undergo noninvasive assessments to track disease progression and understand the underlying mechanisms that could be targeted for future therapies. The goal is to develop strategies to halt the progression of COPD before it becomes irreversible.
Who could benefit from this research
Good fit: Ideal candidates for this research include younger smokers who may be at risk for developing COPD.
Not a fit: Patients with advanced COPD or those who do not smoke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that modify the course of COPD, improving outcomes for patients.
How similar studies have performed: Other research has shown promise in understanding early COPD pathology, but this approach is innovative in its focus on noninvasive detection and immune response analysis.
Where this research is happening
WORCESTER, UNITED STATES
- UNIV OF MASSACHUSETTS MED SCH WORCESTER — WORCESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARTINEZ, FERNANDO J — UNIV OF MASSACHUSETTS MED SCH WORCESTER
- Study coordinator: MARTINEZ, FERNANDO J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.