Exploring the benefits of peptides from human milk for preterm infants' gut health
Defining bioactivities of peptides released from human milk proteins in the preterm infant intestine
This study is looking at how special proteins in human milk can help the intestines of preterm babies grow healthier, by finding out which helpful substances are released during digestion and how they support gut health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11170018 on NIH RePORTER |
What this research studies
This research investigates how bioactive peptides released from human milk proteins can positively affect the intestines of preterm infants. By analyzing the specific peptides that emerge during digestion, the study aims to understand their roles in promoting gut health, including their antimicrobial and immunomodulatory properties. The research will involve collecting and examining intestinal fluid from preterm infants to identify these beneficial peptides and their effects on gut physiology. Ultimately, the goal is to enhance the growth and development of preterm infants through improved nutrition derived from human milk.
Who could benefit from this research
Good fit: Ideal candidates for this research are preterm infants who are receiving human milk, either from their mothers or as pasteurized donor milk.
Not a fit: Patients who are not preterm infants or those who are not receiving human milk may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved nutritional strategies that enhance gut health and overall development in preterm infants.
How similar studies have performed: Previous research has shown promising results in understanding the benefits of human milk for infant health, making this approach both relevant and potentially impactful.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Scottoline, Brian — Oregon Health & Science University
- Study coordinator: Scottoline, Brian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.