Exploring supplements to treat depression and anxiety
Evaluation of Bioenergetic Supplements in Treatment-Resistant Depression, Cognitive Dysfunction and Anxiety
['FUNDING_R01'] · UNIVERSITY OF UTAH · NIH-11171639
This study is looking at whether taking certain supplements, like creatine and acetyl-L carnitine, can help people with depression and anxiety who haven't found relief from regular medications, especially by improving their thinking and mood.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-11171639 on ClinicalTrials.gov |
What this research studies
This research investigates the use of bioenergetic supplements, specifically creatine and acetyl-L carnitine, to treat treatment-resistant depression and anxiety. It focuses on understanding how these supplements can improve cognitive function and alleviate symptoms in individuals who do not respond to traditional antidepressants. The study utilizes a unique animal model that simulates the effects of living at high altitudes, where brain bioenergetic deficits are more pronounced. By examining the efficacy of these compounds, the research aims to provide new therapeutic options for patients suffering from these debilitating conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing treatment-resistant depression or anxiety.
Not a fit: Patients who are currently responding well to traditional antidepressant therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer new treatment options for patients with depression and anxiety who have not benefited from existing medications.
How similar studies have performed: Previous research has shown promise in using bioenergetic compounds for treating mood disorders, indicating potential for success in this novel approach.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KANEKAR, SHAMI — UNIVERSITY OF UTAH
- Study coordinator: KANEKAR, SHAMI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.