Exploring sugar patterns on bacterial surfaces
MIRA: Probing Glycan Polymer Patterns on Bacterial Cell Surfaces
This study is exploring the special sugars on bacteria that help tell them apart and how they cause infections, with the goal of creating new tools to better understand and fight harmful bacteria.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10884464 on NIH RePORTER |
What this research studies
This research investigates the unique sugar polymers found on the surfaces of bacteria, which play a crucial role in distinguishing different bacterial strains and their ability to cause infections. By developing chemical tools, the research aims to manipulate these sugar patterns to better understand how bacteria survive and interact with their hosts. The approach includes creating small molecules that can regulate bacterial functions and selectively label or disable harmful bacteria. This work is essential for advancing our knowledge of bacterial infections and developing new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from infections caused by Gram-negative bacteria.
Not a fit: Patients with infections caused by Gram-positive bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new methods for targeting and treating bacterial infections more effectively.
How similar studies have performed: Other research has shown promise in manipulating bacterial surface structures, indicating potential for success in this area.
Where this research is happening
New York, United States
- New York University — New York, United States (Active)
Researchers
- Principal investigator: Lupoli, Tania — New York University
- Study coordinator: Lupoli, Tania
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.