Exploring sound-based drug delivery methods for inner ear treatment

Mass transport in the inner-ear fluid

NIH-funded research University of Rochester · NIH-10992163

This study is exploring a new way to deliver medicine directly to the inner ear using sound waves, which could help people with inner ear conditions get better treatment without needing invasive procedures.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10992163 on NIH RePORTER

What this research studies

This research investigates innovative ways to deliver medications directly to the inner ear using sound waves. The inner ear is unique because its fluids are stationary and isolated, making traditional drug delivery methods ineffective. By utilizing acoustic stimulation, the researchers aim to create a minimally invasive technique that enhances drug distribution within the inner ear, potentially improving treatment outcomes for various inner ear conditions. This approach seeks to overcome the challenges posed by the blood-labyrinth barrier and the complex geometry of the inner ear.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing inner ear-related health issues.

Not a fit: Patients with conditions unrelated to inner ear health or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for inner ear diseases with fewer side effects.

How similar studies have performed: While the use of sound for drug delivery is a novel approach, similar techniques in other areas of medicine have shown promise, indicating potential for success.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.