Exploring small molecules in biological samples to find disease biomarkers
Systems Metabolomics for Biomarker Discovery
This study is exploring new ways to analyze tiny molecules in biological samples to better understand how they relate to different diseases, with the goal of finding reliable markers that can help in diagnosing and treating those conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-10909945 on NIH RePORTER |
What this research studies
This research investigates the use of advanced techniques like liquid chromatography and gas chromatography coupled with mass spectrometry to analyze thousands of small molecules in biological samples. By employing systems biology approaches, the study aims to uncover the relationships between these metabolites and various diseases. The research focuses on developing new computational tools to accurately identify metabolites and integrate their profiles with other biological data, ultimately enhancing the discovery of reliable biomarkers for diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with specific diseases that may be linked to metabolite changes, as well as those interested in contributing to biomarker discovery efforts.
Not a fit: Patients who do not have any metabolic disorders or are not involved in the targeted diseases may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to the identification of more accurate and generalizable biomarkers for various diseases, improving diagnosis and treatment options for patients.
How similar studies have performed: Previous research in metabolomics has shown promise in identifying disease biomarkers, suggesting that this approach could yield significant advancements in the field.
Where this research is happening
Washington, United States
- Georgetown University — Washington, United States (Active)
Researchers
- Principal investigator: Ressom, Habtom W — Georgetown University
- Study coordinator: Ressom, Habtom W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.